Corticofugal influence in the macaque lateral geniculate nucleus.
نویسنده
چکیده
Responses of single cells in the macaque lateral geniculate nucleus were recordedthrough extracelltiar micropipettes. Spectral sensitivity of each cell was determined byrecording its responses to 6 diffuse monochromatic photic stimuli. Activity in a pre-determined limited area of striate cortex was then temporarily removed by cooling andresponses to the same photic stimuli were recorded. Responses of approximately half theunits projecting to the cooled cortical area were altered during cooling. A decrease inresponses to excitatory stimuli was predominant, implying removal of corticofugalexcitation. Some cells increased their responses to excitatory stimuli during dortical cooling,implying removal of corticofugal inhibition. R∑&Gn; enregistre avec des micropipettes extracellulaires lea reponses de cellulesisoltks du corps lateral genouille chez le macaque. On determine la sensibilite spectralede chaque cellule en recueillant les reponses 51 6 stimuli monochromatiques diffus. Ensuiteon supprimait temporairement l’activite dans une aire 1imitQ du cortex strie en la re1298EI,A~NEM. HULL froidissant et on enregistrait les reponses aux memes stimuli lumineux. Durant lerefroidissement, les rt!sponses d’environ la moitie des unites qui se projetaient dam l’airecorticale mfroidie se trouvaient ah&&s.; En major% on constatait une diminution damdans lea reponses aux stimuli excitants, ce qui implique la suppression dune excitationcorticofuge. Quelques celhdes augmentaient leurs reponses aux stimuli excitants durant lerefroidissement cortical, ce qui implique la suppression d’une inhibition corticofuge. Zusammenfassung-Die Antworten von Einzelzellen vom LGN des Macaque Affen wurdendurch extrazelhdlre Mikropipettenelektroden abgeleitet. Die spektrale Empfindlichkeiteiner jeden Zelle wurde dadurch bestimmt, da13 ihre Antworten auf 6 diffuse, monochro-matische Lichtreize aufgenommen wurden. Die Aktivitat in einem vorbestimmten,beschrlnkten Gebiet des Cortex Striatum wurde dann durch Ktihlung zeitweise unterbundenund die Antworten auf die selben Lichtreize aufgenommen. Die Antworten von ungefahrder H&lfte; der Einheiten, die zu dem gektihlten kortikalen Gebiet hinwiesen, wurdenwahrend der Abktihhmg verandert. Die Abnahme der Antworten auf excitatorische Reizewar predominant, was auf eine Reseitigung kortigofugaler Reizung schlieBen Wt. EinigeZellen versttikten ihre Antworten auf exzitatorische Reize wahrend der Ktihlung desKortex, woraus eine Reseitigung der kortigofugalen Inhibition gefolgert wird. Pt23IOMe hXU@Di OTAeJIbHbIX KJICTOK B SLApaX JIaTepanbHbIX ICOJICHYaTbIXTeJlMaKaICH 6br.m 3apWZiCTpHpOBaHbI 3KCTpaKJIeTO=IHO C IlOMOIIIbIO 3JIeKTpOAOB -MHKpOllEUeTOK. CIIeKTpaJIbHaX ¶)'BCTBHTC&HOCTb; KaxAOii KJICTKH 6bIna OIIpeAe-JIeHa nyTeM 3iUlECH e peaKI@% Ha 6 AE@&3HbIX MOIiOXpOMBTWICCKEIX CBeTOBbIXCTliMyJIOB. 3arebr aKmmcrb npe~aapnrenbrro 0npeAenennotr orpamirerrrror?o6nacr-n CTpHFipHOti KOpbI 6bma BpeMeHHO BbIKJIKYIeHa OXJIaXCAeHEM H CHOBa3a~~~I~~~H~T~~eCaMbIeCBCTOBbI~C~~b~.~C~~~p~6~~3~Te~HoIIOJlOBHHbI KJIeTOK, HMUOUUIX npOeK_ B OXlIa~eHHOi% KOpTHKaJlbHOti 06naCm,6~rrrr H3MtXeHbI BO BpeMR OxnaXc~eHHSI. Hpeo6naAano IIOHu)KeHHB pWKUIiti HaBo36yHssamque CTUM)'JlbI,ST0 npe~onomTenbH0oseaqano BbIKJHOYeHHe K~PTH-KO&WIbHO;~O Bo36yxAeHwx. HeKOTOpbIe KlIeTKSi~eJIWiEE4aJIH CBOH peaKWiH HaBo36malorqHe CWhQVIbI, WO MOrJlO 03HaYaTb BbIKJIKVEH~e KOpTHKO~yEUlbHO~O
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عنوان ژورنال:
- Vision research
دوره 8 10 شماره
صفحات -
تاریخ انتشار 1968